Nephron+ prototype presentation at World Kidney Day 2013

March 22, 2013

On the occasion of the World Kidney Day (14-03-2013) the UMCU (NL) organized a public lecture session together with demo’s and a panel discussion.  The session was chaired by dr. Walter Boer and lectures were held by prof. Marianne Verhaar on “renal replacement therapies: past, present and future” and by dr. Karin Gerritsen on “new developments in dialysis”. The lectures attracted more than 70 interested participants which was considered to be very good since this event was organized for the first time and it was held at evening hours (19.00-22.00 hrs), 

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Maarten Wester (UMCU) at the WKD 2013 explaining the Nephron+ wearable artificial kidney, attached to mannequin Rinus

 The Nephron+ project was highlighted by Karin Gerritsen during here lecture. Maarten Wester (UMCU) and Frank Simonis (NANO) had prepared a demo showing the Nephron+ wearable artificial kidney prototype in operation and showing the possible wearability of such a device. They  received enthusiastic feedback from the audience. This was followed by a very vivid discussion during the panel discussion. The demo stand of Nephron+ was accompanied by stands of the Nierstichting (Dutch Kidney Foundation) and the NVN (Dutch association of renal patients).

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Enthusiastic audience visiting the demo area

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Nephron+ engineering prototype in action


Microfluidic Electronic Sub-System Demostration

May 31, 2012

A demonstrator that contains the RTMCB integrating the Physical Sensors, the ECPs, the Actuators and the Polarizer is shown in the following video. This sub-system is controlled by a PC testing program (developed by CSEM) by means of a IFRS422 module (USB-PTP RS422 link).


NEPHRON+ Smartphone Application First Version Presentation

May 31, 2012

The following video presents the basic features of the first version of the smartphone application (developed by EXODUS S.A). Through the options provided the user can check his/her measurements, send remote commands like change state or shutdown to the Wearable Artificial Kidney Device (WAKD), define notable upcoming events to the agenda for which reminders will be produced and adjust the interface according to his/her personal tastes. The development of this application is in progress, so new features will be availabe soon for which you will be informed from this blog and from NEPHRON+ website.


Microfluidic Electronic Subsystem Integrated

May 30, 2012

A demonstrator that contains the Reat Time Microfluidic Circuit Board (RTMCB) integrating the physical sensors, the Electrochemical platform, the actuators and the polarizer is shown in the picture below. This sub-system is controlled by a PC testing program (developed by CSEM) by means of a IFRS422 module (USB-PTP RS422 link).

A demonstrator that contains the RTMCB integrating the Physical Sensors, the ECPs, the Actuators and the Polarizer is shown in the following video:

For more information you may visit NEPHRON+ site.


First version of mobile application NEPHRON+ released!

May 9, 2012

The first version of the mobile application has been released. The mobile application is a main point of interaction between the patient and the system. This version supports the communication between the mobile device and the WAKD as well as various control features of the device. Moreover it provides graphical and tabular representation of measurements and it is capable of producing reminders and alerts when needed.  All operations are available through a friendly user interface (see screenshots). The first version of the mobile application has been already delivered to users in order to get evaluation feedback that will be used in later stage for improving the application and developing new features included to the second version of the application.

For more details check NEPHRON+ site.


Nephron+ prototype tested at Danube Univ. Krems

May 9, 2012

During April 11-12th 2012 in-vitro tests were carried at the labs of the University of Krems (Austria), partner in Nephron+. The engineering prototype of the WAKD was tested against human blood. A large set of parameters have been analysed covering the clearance performance as well as the biocompatibility of the prototype. Next to concentration profiles of Na, K, Ca, Mg, PO4, urea, creatinine and pH also hemolysis, oxidative stress and the cytotoxicity have been measured. Good results have been obtained as can be seen in the pictures below. In order to study the reproducibility, more in-vitro tests at Krems are planned for June next coming.

For more details check NEPHRON+ site.


OVP-Simulink interfacing code for co-simulation published

December 14, 2011

Project partner OFFIS has implemented, as part of the project, an interface between the Open Virtual Platform and Matlab Simulink for co-simulation purposes. The source code to this development has now been published online, and significant interest has been generated within the OVP community. Specific NEPHRON+ results with relevance to this co-simulation environment have also been published.


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